regarding the Amitriptyline, my psych currently has me on 50mg at night. it is so sedating and brain fogging for me. i'm a mess until early afternoon. and it sure isnt doing much for my depression. havent left house in a few days. did you experience this too? I wish you luck on this painful journey of depression. HappyoneMy first was Tofranil. Then Amiptrypline. Then Prozac. Then Paxil. Then Effexor. Then Zoloft. Then a combination of Lexapro and Wellbutrin, which I'm currently on.