An I going to kill my tolerance level if I start regularly plugging instead of swallowing my morphine? Because i AM NOT getting enough relief!!Yes. Plugging may be the most effective way to administer morphine, as it avoids the histamine rush of iv. Oral BA is about 10% compared to 70-90% rectally.
YOU TOTALLY IGNORED MY QUESTION DUMMY!!! TRY AGAIN!!! PLEASE RE-READ MY QUESTION!!! I NEED TO KNOW!!!.... HERE IN CASE YOU CAN'T FIND MY QUESTION!!!Yes. Plugging may be the most effective way to administer morphine, as it avoids the histamine rush of iv. Oral BA is about 10% compared to 70-90% rectally.
An I going to kill my tolerance level if I start regularly plugging instead of swallowing my morphine? Because i AM NOT getting enough relief!!
You will likely find your tolerance rise if you plug regularly because so much more morphine is absorbed and cyclizine potentiates opioids so effectively (watch out dose wise and read Trainspotting) it was made prescription only in UK. Seems to potentiate methadone and analogues (dipipanone etc) in particular so double careful folks.In exactly the same situation. Not noticed my tolerance go up at all! And I feel close to twice the pain relief when plugging vs swallowing orally.
Just make sure you crush up the morphine into as fine a powder as possible and give it a little time to FULLY dissolve in the water.
You will likely find your tolerance rise if you plug regularly because so much more morphine is absorbed and cyclizine potentiates opioids so effectively (watch out dose wise and read Trainspotting) it was made prescription only in UK. Seems to potentiate methadone and analogues (dipipanone etc) in particular so double careful folks.