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MAM-2201 or (1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole) is a research chemical that acts as an agonist at both cannabinoids receptors. It is unclear who AB-001 was originally developed by, and no information has been published on its receptor binding or pharmacological profile, but it is structurally related to compounds such as AM-2201 and JWH-122. There have been anecdotal reports of individuals experiencing panic attacks and vomiting, at doses as small as 2 milligrams. As the dosage is much smaller than most other synthetic cannabinoids, users may accidentally dose too much. Caution should be taken if using this substance as it is active at doses as small as 500 µg (micrograms), has a very steep dose-response curve, and tolerance builds up quickly to the effects. As of November 2011, there have been no reports of death associated with the drug. The toxicity of AM-2201 is still a matter of debate, and there is no certainty of long-term side effects.

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